There are many drugs available in the market that helps with hypertension. Hypertension basically means high blood pressure. Doxazosin Mesylate is a α1adrenergic blocking agent. It is mainly used for managing hypertension. Doxazosin Mesylate can be administered alone or along with another anti-hypertensive agent. Note that it may have potential favorable effects in hypertensive people that possess benignprostatic hyperplasia or any other kind of urinary outflow obstruction. It is commonly sold under the brand names Cardura or Carduran. Another use of this drug is to reduce urinary obstruction. Also to relief any associated manifestations. Surgery may be provide better results when it comes to Benign Prostatic Hyperplasia (BPH), however, Doxazosin Mesylate can provide less adverse effects that surgery can cause. A patient may also consider combining therapy with this medication to make it more effective.
Doxasozin Mesylate is usually administrated orally. Doctors usually prescribe a once a day administration only, either one in the morning or one at night. The effect of your food intake in maxima plasma concentration and AUC is not of clinical importance.
Dosage will be altered according to the patient’s tolerance and response to the drug. Therefore, a series of tests will be required to before a person can take this medicine. Otherwise, it may create unexpected effects. Side effects are usually postural hypotension or in some cases syncope. To minimize these effects, make sure that you keep your initial dosage at a minimum. If in case postural hypotension will appear, it will take 2-6 hours before the patient can feel its symptoms. This is the reason why a professional should closely be monitoring the patient and his blood pressure after the first dose and as the dose increases. If the patient has therapy and has been interrupted, restart by using the initial dosage again. Do not pick up from where you left off.
For paediatric patients, the initial dosage is 1mg once a day. As this dosage increases, the patient will be allowed to take as much as 4mg once in a day. But this increase in dosage must be done only when necessary. Again, this decision will depend on the paediatrician or cardiologist. For adults who are suffering from hypertension, the same initial dosage is applied – 1mg once in a day. It will depend on the patient’s progress and vitals if he or she can take more than the suggested initial dosage. Keep track of your patient and make subsequent increases in dosage for the next weeks to one month until the desired blood pressure control is already achieved. In instances that the drug is not tolerated, consult an expert immediately. An adult can take up to 16mg of Doxazosin Mesylate in a day but with the proper supervision.
On February 22, 2005, the US FDA approved a sustained release form of doxazosin, to be marketed as Cardura XL.”